HCSGD entry for NFU1
1. General information
| Official gene symbol | NFU1 |
|---|---|
| Entrez ID | 27247 |
| Gene full name | NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) |
| Other gene symbols | HIRIP HIRIP5 MMDS1 NIFUC Nfu NifU |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0016226 | Iron-sulfur cluster assembly | IDA IEA | biological_process |
| GO:0051536 | Iron-sulfur cluster binding | IEA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6074675962 | 0.6977369591 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1454400363 |
| GSE13712_SHEAR | Up | 0.0336938920 |
| GSE13712_STATIC | Up | 0.1771969089 |
| GSE19018 | Up | 0.1994735163 |
| GSE19899_A1 | Up | 0.0961286955 |
| GSE19899_A2 | Up | 0.0148704392 |
| PubMed_21979375_A1 | Up | 0.2439380443 |
| PubMed_21979375_A2 | Down | -0.0168813193 |
| GSE35957 | Down | -0.1706916250 |
| GSE36640 | Up | 0.3786623806 |
| GSE54402 | Up | 0.1586872081 |
| GSE9593 | Down | -0.0845115929 |
| GSE43922 | Up | 0.0153623519 |
| GSE24585 | Down | -0.2290636982 |
| GSE37065 | Down | -0.0756473482 |
| GSE28863_A1 | Down | -0.1073291172 |
| GSE28863_A2 | Down | -0.0224402134 |
| GSE28863_A3 | Down | -0.2931246266 |
| GSE28863_A4 | Down | -0.1470430740 |
| GSE48662 | Up | 0.0739275562 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028517 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048651 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052291 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
