HCSGD entry for RND1
1. General information
| Official gene symbol | RND1 |
|---|---|
| Entrez ID | 27289 |
| Gene full name | Rho family GTPase 1 |
| Other gene symbols | ARHS RHO6 RHOS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005912 | Adherens junction | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007015 | Actin filament organization | IDA | biological_process |
| GO:0007162 | Negative regulation of cell adhesion | IDA | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016322 | Neuron remodeling | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0659152122 | 0.9814465142 | 0.5534144498 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1672238034 |
| GSE13712_SHEAR | Up | 0.3192274022 |
| GSE13712_STATIC | Up | 0.7923571992 |
| GSE19018 | Up | 0.1261565960 |
| GSE19899_A1 | Up | 0.1741649890 |
| GSE19899_A2 | Up | 0.1709867296 |
| PubMed_21979375_A1 | Down | -0.0030135697 |
| PubMed_21979375_A2 | Down | -0.1540075615 |
| GSE35957 | Down | -0.0843864428 |
| GSE36640 | Up | 0.0500837625 |
| GSE54402 | Down | -0.0229747189 |
| GSE9593 | Up | 0.1541782895 |
| GSE43922 | Up | 0.0139806553 |
| GSE24585 | Up | 0.7787860527 |
| GSE37065 | Up | 0.0529645067 |
| GSE28863_A1 | Up | 0.0140921570 |
| GSE28863_A2 | Up | 0.0304984515 |
| GSE28863_A3 | Up | 0.4523965821 |
| GSE28863_A4 | Up | 0.2052157010 |
| GSE48662 | Up | 0.2035947550 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021868 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
