HCSGD entry for PDLIM3
1. General information
| Official gene symbol | PDLIM3 |
|---|---|
| Entrez ID | 27295 |
| Gene full name | PDZ and LIM domain 3 |
| Other gene symbols | ALP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007015 | Actin filament organization | IEA | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008307 | Structural constituent of muscle | IEA | molecular_function |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0030018 | Z disc | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9092295354 | 0.0649163862 | 0.9999902473 | 0.4809074585 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1521881009 |
| GSE13712_SHEAR | Up | 0.0306534218 |
| GSE13712_STATIC | Down | -0.0456941137 |
| GSE19018 | Up | 0.0997111141 |
| GSE19899_A1 | Down | -0.3020742858 |
| GSE19899_A2 | Down | -0.3101122070 |
| PubMed_21979375_A1 | Down | -0.2278933596 |
| PubMed_21979375_A2 | Down | -0.3961807786 |
| GSE35957 | Up | 0.1321344593 |
| GSE36640 | Down | -0.7317771391 |
| GSE54402 | Up | 0.0140385358 |
| GSE9593 | Up | 0.0128428844 |
| GSE43922 | Up | 0.1620367925 |
| GSE24585 | Up | 0.1370326821 |
| GSE37065 | Down | -0.2648342056 |
| GSE28863_A1 | Up | 0.0839326294 |
| GSE28863_A2 | Up | 0.1376960610 |
| GSE28863_A3 | Down | -0.0720172126 |
| GSE28863_A4 | Down | -0.0131845824 |
| GSE48662 | Down | -0.3259134045 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024819 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026792 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
