HCSGD entry for ANGPTL3

1. General information

Official gene symbolANGPTL3
Entrez ID27329
Gene full nameangiopoietin-like 3
Other gene symbolsANG-5 ANGPT5 ANL3 FHBL2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004857Enzyme inhibitor activityISSmolecular_function
GO:0004859Phospholipase inhibitor activityIDAmolecular_function
GO:0005178Integrin bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0006071Glycerol metabolic processIDAbiological_process
GO:0006631Fatty acid metabolic processIDAbiological_process
GO:0006644Phospholipid metabolic processIDAbiological_process
GO:0007160Cell-matrix adhesionIPIbiological_process
GO:0007165Signal transductionIDAbiological_process
GO:0007229Integrin-mediated signaling pathwayNASbiological_process
GO:0008083Growth factor activityIDAmolecular_function
GO:0008203Cholesterol metabolic processIDAbiological_process
GO:0009395Phospholipid catabolic processIDAbiological_process
GO:0009725Response to hormoneIEAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0010519Negative regulation of phospholipase activityIDAbiological_process
GO:0019915Lipid storageIDAbiological_process
GO:0030335Positive regulation of cell migrationIDAbiological_process
GO:0042632Cholesterol homeostasisIDAbiological_process
GO:0045766Positive regulation of angiogenesisIDAbiological_process
GO:0048844Artery morphogenesisISSbiological_process
GO:0050996Positive regulation of lipid catabolic processIDAbiological_process
GO:0051005Negative regulation of lipoprotein lipase activityIDAbiological_process
GO:0055088Lipid homeostasisIDAbiological_process
GO:0055090Acylglycerol homeostasisIDAbiological_process
GO:0055091Phospholipid homeostasisIDAbiological_process
GO:0070328Triglyceride homeostasisIGI ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85909202160.81698633030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0155791112
GSE13712_SHEARDown-0.0341685425
GSE13712_STATICUp0.0531961074
GSE19018Up0.0627646545
GSE19899_A1Down-0.0077656564
GSE19899_A2Down-0.0144047575
PubMed_21979375_A1Up0.0235780363
PubMed_21979375_A2Down-0.0255284486
GSE35957Up0.0908851194
GSE36640Up0.0278961921
GSE54402Up0.0658002285
GSE9593Down-0.0050491112
GSE43922Up0.0222188060
GSE24585Down-0.1376860952
GSE37065Up0.0094439621
GSE28863_A1Up0.0009949902
GSE28863_A2Down-0.0049455120
GSE28863_A3Up0.1078336562
GSE28863_A4Down-0.1030648128
GSE48662Up0.1020291235

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.