HCSGD entry for GNB2
1. General information
| Official gene symbol | GNB2 |
|---|---|
| Entrez ID | 2783 |
| Gene full name | guanine nucleotide binding protein (G protein), beta polypeptide 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005246 | Calcium channel regulator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0032403 | Protein complex binding | IDA | molecular_function |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0044297 | Cell body | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0051020 | GTPase binding | IPI | molecular_function |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6010500855 | 0.4759868318 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0696185950 |
| GSE13712_SHEAR | Down | -0.1160901648 |
| GSE13712_STATIC | Down | -0.0717005815 |
| GSE19018 | Up | 0.1672622643 |
| GSE19899_A1 | Down | -0.3891575461 |
| GSE19899_A2 | Up | 0.5209484601 |
| PubMed_21979375_A1 | Down | -0.1317312048 |
| PubMed_21979375_A2 | Down | -0.0914657265 |
| GSE35957 | Down | -0.4640770621 |
| GSE36640 | Up | 0.0170484748 |
| GSE54402 | Up | 0.1244608041 |
| GSE9593 | Up | 0.0125403663 |
| GSE43922 | Up | 0.0001668176 |
| GSE24585 | Up | 0.1522361205 |
| GSE37065 | Down | -0.2319886063 |
| GSE28863_A1 | Up | 0.0740139490 |
| GSE28863_A2 | Up | 0.0872556200 |
| GSE28863_A3 | Up | 0.0230168441 |
| GSE28863_A4 | Down | -0.1380835881 |
| GSE48662 | Up | 0.3568526176 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023870 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037626 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040606 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041719 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043102 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043396 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050393 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051197 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
