HCSGD entry for GNG5
1. General information
| Official gene symbol | GNG5 |
|---|---|
| Entrez ID | 2787 |
| Gene full name | guanine nucleotide binding protein (G protein), gamma 5 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0004871 | Signal transducer activity | NAS | molecular_function |
| GO:0005834 | Heterotrimeric G-protein complex | NAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | NAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0030165 | PDZ domain binding | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0071377 | Cellular response to glucagon stimulus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3655455112 | 0.7578677710 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1746998623 |
| GSE13712_SHEAR | Up | 0.0323546238 |
| GSE13712_STATIC | Up | 0.0720201550 |
| GSE19018 | Down | -0.1685201097 |
| GSE19899_A1 | Down | -0.0202223562 |
| GSE19899_A2 | Down | -0.0059013792 |
| PubMed_21979375_A1 | Up | 0.5480410458 |
| PubMed_21979375_A2 | Up | 0.1654036653 |
| GSE35957 | Down | -0.5994556125 |
| GSE36640 | Up | 0.1449031777 |
| GSE54402 | Up | 0.4457229143 |
| GSE9593 | Up | 0.0030722909 |
| GSE43922 | Up | 0.1217782221 |
| GSE24585 | Up | 0.1319427660 |
| GSE37065 | Up | 0.2331017109 |
| GSE28863_A1 | Up | 0.1141533004 |
| GSE28863_A2 | Up | 0.1761963624 |
| GSE28863_A3 | Down | -0.2158490165 |
| GSE28863_A4 | Down | -0.2987226312 |
| GSE48662 | Down | -0.3035616090 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023505 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027504 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028436 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048451 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051558 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
