HCSGD entry for GPD1
1. General information
| Official gene symbol | GPD1 |
|---|---|
| Entrez ID | 2819 |
| Gene full name | glycerol-3-phosphate dehydrogenase 1 (soluble) |
| Other gene symbols | GPD-C GPDH-C HTGTI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004367 | Glycerol-3-phosphate dehydrogenase [NAD+] activity | IEA | molecular_function |
| GO:0004368 | Glycerol-3-phosphate dehydrogenase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006094 | Gluconeogenesis | IEA | biological_process |
| GO:0006116 | NADH oxidation | IEA | biological_process |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0009331 | Glycerol-3-phosphate dehydrogenase complex | IEA | cellular_component |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046168 | Glycerol-3-phosphate catabolic process | IEA | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0051287 | NAD binding | IEA | molecular_function |
| GO:0071320 | Cellular response to cAMP | IEA | biological_process |
| GO:0071356 | Cellular response to tumor necrosis factor | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7650582843 | 0.6854350671 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0254914990 |
| GSE13712_SHEAR | Down | -0.0967962024 |
| GSE13712_STATIC | Down | -0.0746768074 |
| GSE19018 | Up | 0.1495770519 |
| GSE19899_A1 | Up | 0.0881693957 |
| GSE19899_A2 | Down | -0.0897766378 |
| PubMed_21979375_A1 | Down | -0.0217247399 |
| PubMed_21979375_A2 | Down | -0.1075101783 |
| GSE35957 | Up | 0.1524081044 |
| GSE36640 | Down | -0.0132965824 |
| GSE54402 | Up | 0.0501790481 |
| GSE9593 | Down | -0.3198542483 |
| GSE43922 | Up | 0.0526102219 |
| GSE24585 | Down | -0.3163193049 |
| GSE37065 | Up | 0.0569566705 |
| GSE28863_A1 | Down | -0.0503257275 |
| GSE28863_A2 | Down | -0.1224392036 |
| GSE28863_A3 | Up | 0.2556076142 |
| GSE28863_A4 | Up | 0.1833900387 |
| GSE48662 | Up | 0.0210370799 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-103a-3p | MIMAT0000101 | MIRT001842 | Luciferase reporter assay | Non-Functional MTI | 15131085 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
