HCSGD entry for ANK3

1. General information

Official gene symbolANK3
Entrez ID288
Gene full nameankyrin 3, node of Ranvier (ankyrin G)
Other gene symbolsANKYRIN-G
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000281Mitotic cytokinesisIMPbiological_process
GO:0005200Structural constituent of cytoskeletonIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005764LysosomeIEAcellular_component
GO:0005886Plasma membraneISScellular_component
GO:0005923Tight junctionIDAcellular_component
GO:0007009Plasma membrane organizationIMPbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0007409AxonogenesisISSbiological_process
GO:0007411Axon guidanceIEAbiological_process
GO:0007528Neuromuscular junction developmentIEAbiological_process
GO:0008092Cytoskeletal protein bindingISSmolecular_function
GO:0009925Basal plasma membraneIDAcellular_component
GO:0009986Cell surfaceISScellular_component
GO:0010628Positive regulation of gene expressionISSbiological_process
GO:0010650Positive regulation of cell communication by electrical couplingIEAbiological_process
GO:0010765Positive regulation of sodium ion transportISSbiological_process
GO:0014704Intercalated discIEA ISScellular_component
GO:0014731Spectrin-associated cytoskeletonISScellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0016328Lateral plasma membraneIDAcellular_component
GO:0016529Sarcoplasmic reticulumIEAcellular_component
GO:0019228Neuronal action potentialIEA ISSbiological_process
GO:0030018Z discIEAcellular_component
GO:0030315T-tubuleISScellular_component
GO:0030425DendriteIEAcellular_component
GO:0030507Spectrin bindingISSmolecular_function
GO:0030674Protein binding, bridgingISSmolecular_function
GO:0031594Neuromuscular junctionIEAcellular_component
GO:0033268Node of RanvierIEA ISScellular_component
GO:0033270Paranode region of axonIEAcellular_component
GO:0034112Positive regulation of homotypic cell-cell adhesionIEAbiological_process
GO:0042383SarcolemmaIDAcellular_component
GO:0043001Golgi to plasma membrane protein transportIMPbiological_process
GO:0043034CostamereTAScellular_component
GO:0043194Axon initial segmentIEA ISScellular_component
GO:0043266Regulation of potassium ion transportISSbiological_process
GO:0044325Ion channel bindingISSmolecular_function
GO:0045184Establishment of protein localizationIMPbiological_process
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045296Cadherin bindingISSmolecular_function
GO:0045838Positive regulation of membrane potentialISSbiological_process
GO:0071709Membrane assemblyIMPbiological_process
GO:0072659Protein localization to plasma membraneIGI IMPbiological_process
GO:0072660Maintenance of protein location in plasma membraneIGIbiological_process
GO:0072661Protein targeting to plasma membraneIEA IMPbiological_process
GO:0090314Positive regulation of protein targeting to membraneIEAbiological_process
GO:1900827Positive regulation of membrane depolarization during cardiac muscle cell action potentialISSbiological_process
GO:2000651Positive regulation of sodium ion transmembrane transporter activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00367061280.95199521290.16317432891.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3289938420
GSE13712_SHEARUp0.0865693751
GSE13712_STATICDown-0.0042665977
GSE19018Up0.0764172506
GSE19899_A1Up0.2449876683
GSE19899_A2Up1.4170872583
PubMed_21979375_A1Up1.1063471229
PubMed_21979375_A2Up1.6904966530
GSE35957Up0.8242356655
GSE36640Up0.7113709322
GSE54402Up1.1432082921
GSE9593Down-0.1116525660
GSE43922Up1.8892752739
GSE24585Up0.1675926182
GSE37065Down-0.6345261481
GSE28863_A1Down-0.0323275542
GSE28863_A2Down-0.0259348001
GSE28863_A3Up0.0982757454
GSE28863_A4Up0.0416527547
GSE48662Up0.1057836857

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.