HCSGD entry for GRIA4
1. General information
| Official gene symbol | GRIA4 |
|---|---|
| Entrez ID | 2893 |
| Gene full name | glutamate receptor, ionotropic, AMPA 4 |
| Other gene symbols | GLUR4 GLUR4C GLURD GluA4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004970 | Ionotropic glutamate receptor activity | IEA ISS | molecular_function |
| GO:0004971 | Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | IDA | molecular_function |
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005234 | Extracellular-glutamate-gated ion channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0007215 | Glutamate receptor signaling pathway | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0030666 | Endocytic vesicle membrane | TAS | cellular_component |
| GO:0032281 | Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex | IEA ISS | cellular_component |
| GO:0034220 | Ion transmembrane transport | IDA ISS | biological_process |
| GO:0035235 | Ionotropic glutamate receptor signaling pathway | IDA ISS | biological_process |
| GO:0045202 | Synapse | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | IDA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9648152274 | 0.1492764181 | 0.9999902473 | 0.7469780608 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0585818535 |
| GSE13712_SHEAR | Up | 0.0728739117 |
| GSE13712_STATIC | Down | -0.1490688475 |
| GSE19018 | Down | -0.0674074947 |
| GSE19899_A1 | Down | -0.0908564772 |
| GSE19899_A2 | Down | -1.1497746725 |
| PubMed_21979375_A1 | Down | -0.1884041399 |
| PubMed_21979375_A2 | Up | 0.0125635799 |
| GSE35957 | Up | 0.0843962629 |
| GSE36640 | Down | -0.2166095292 |
| GSE54402 | Down | -0.2769738694 |
| GSE9593 | Down | -0.0037940784 |
| GSE43922 | Down | -0.4776237591 |
| GSE24585 | Up | 0.2223878332 |
| GSE37065 | Down | -0.0416911148 |
| GSE28863_A1 | Down | -0.0648626249 |
| GSE28863_A2 | Down | -0.2341313904 |
| GSE28863_A3 | Up | 0.1848190555 |
| GSE28863_A4 | Up | 0.0487254832 |
| GSE48662 | Down | -0.0754291682 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042105 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
