HCSGD entry for RANGRF

1. General information

Official gene symbolRANGRF
Entrez ID29098
Gene full nameRAN guanine nucleotide release factor
Other gene symbolsHSPC236 MOG1 RANGNRF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002027Regulation of heart rateTASbiological_process
GO:0003254Regulation of membrane depolarizationIDA IMPbiological_process
GO:0005085Guanyl-nucleotide exchange factor activityISSmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmISScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005791Rough endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneICcellular_component
GO:0005901CaveolaIDAcellular_component
GO:0006888ER to Golgi vesicle-mediated transportIMPbiological_process
GO:0008536Ran GTPase bindingIPI ISSmolecular_function
GO:0008565Protein transporter activityIMPmolecular_function
GO:0014704Intercalated discISScellular_component
GO:0017080Sodium channel regulator activityIDA IMPmolecular_function
GO:0032527Protein exit from endoplasmic reticulumIMPbiological_process
GO:0042391Regulation of membrane potentialIDAbiological_process
GO:0043087Regulation of GTPase activityISSbiological_process
GO:0044325Ion channel bindingIPImolecular_function
GO:0090004Positive regulation of establishment of protein localization to plasma membraneIMPbiological_process
GO:1900825Regulation of membrane depolarization during cardiac muscle cell action potentialTASbiological_process
GO:1902305Regulation of sodium ion transmembrane transportIDA IMPbiological_process
GO:2000010Positive regulation of protein localization to cell surfaceIDA IMPbiological_process
GO:2000649Regulation of sodium ion transmembrane transporter activityIDA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98635505870.01110461610.99999024730.2083282965

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2366833318
GSE13712_SHEARDown-0.4257110072
GSE13712_STATICDown-0.0401277351
GSE19018Up0.0268537532
GSE19899_A1Down-0.5484981539
GSE19899_A2Down-0.3081345797
PubMed_21979375_A1Down-0.6360317065
PubMed_21979375_A2Down-0.9240907064
GSE35957Down-0.5799854980
GSE36640Down-0.3214689357
GSE54402Down-0.0353555100
GSE9593Down-0.2130706934
GSE43922Down-0.1579690339
GSE24585Down-0.3222854758
GSE37065Down-0.1032636498
GSE28863_A1Down-0.4021229964
GSE28863_A2Down-0.8400852276
GSE28863_A3Down-0.2095171660
GSE28863_A4Up0.2035457330
GSE48662Down-0.2239717921

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.