HCSGD entry for GRM5

1. General information

Official gene symbolGRM5
Entrez ID2915
Gene full nameglutamate receptor, metabotropic 5
Other gene symbolsGPRC1E MGLUR5 mGlu5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000185Activation of MAPKKK activityIEAbiological_process
GO:0002029Desensitization of G-protein coupled receptor protein signaling pathwayIEAbiological_process
GO:0004930G-protein coupled receptor activityIEA TASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIMPcellular_component
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006468Protein phosphorylationIEAbiological_process
GO:0007205Protein kinase C-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007206Phospholipase C-activating G-protein coupled glutamate receptor signaling pathwayTASbiological_process
GO:0007216G-protein coupled glutamate receptor signaling pathwayIMPbiological_process
GO:0007268Synaptic transmissionIEAbiological_process
GO:0007612LearningIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008066Glutamate receptor activityIDAmolecular_function
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0031687A2A adenosine receptor bindingIEAmolecular_function
GO:0040013Negative regulation of locomotionIEAbiological_process
GO:0043197Dendritic spineIEAcellular_component
GO:0043198Dendritic shaftIEAcellular_component
GO:0048170Positive regulation of long-term neuronal synaptic plasticityIEAbiological_process
GO:0097449Astrocyte projectionIEAcellular_component
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80406456820.85690370810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2243400141
GSE13712_SHEARDown-0.0297245782
GSE13712_STATICDown-0.0429838107
GSE19018Up0.0327328929
GSE19899_A1Up0.0781456545
GSE19899_A2Down-0.0529823290
PubMed_21979375_A1Up0.1507102826
PubMed_21979375_A2Up0.0854268476
GSE35957Up0.1494318076
GSE36640Up0.0024885216
GSE54402Up0.0898832264
GSE9593Down-0.0289256881
GSE43922Up0.0543691166
GSE24585Up0.1258852320
GSE37065Down-0.0173340204
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1104584374

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AcamprosateDB00659 APRD00661
ADX10059DB05070 -
ADX-48621DB06060 -
RufinamideDB06201 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018632MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.