HCSGD entry for CXCL3
1. General information
| Official gene symbol | CXCL3 |
|---|---|
| Entrez ID | 2921 |
| Gene full name | chemokine (C-X-C motif) ligand 3 |
| Other gene symbols | CINC-2b GRO3 GROg MIP-2b MIP2B SCYB3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0008009 | Chemokine activity | ISS | molecular_function |
| GO:0030593 | Neutrophil chemotaxis | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000250104 | 0.4067476654 | 0.0149063830 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 4.5586362613 |
| GSE13712_SHEAR | Down | -0.2913771982 |
| GSE13712_STATIC | Down | -0.1428498492 |
| GSE19018 | Down | -0.4891868998 |
| GSE19899_A1 | Up | 7.2173588361 |
| GSE19899_A2 | Up | 8.5322704212 |
| PubMed_21979375_A1 | Up | 9.0186865834 |
| PubMed_21979375_A2 | Up | 9.1312181570 |
| GSE35957 | Down | -1.3960421376 |
| GSE36640 | Up | 0.3481300716 |
| GSE54402 | Up | 1.1803459608 |
| GSE9593 | Down | -1.2933911932 |
| GSE43922 | Up | 0.5357713965 |
| GSE24585 | Down | -0.0371103373 |
| GSE37065 | Up | 0.6676044593 |
| GSE28863_A1 | Up | 0.5681760174 |
| GSE28863_A2 | Up | 0.2231829467 |
| GSE28863_A3 | Up | 0.1502663474 |
| GSE28863_A4 | Down | -0.1579991428 |
| GSE48662 | Up | 0.0292510286 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT005823 | Microarray | Functional MTI (Weak) | 21282569 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018278 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1 | MIMAT0000416 | MIRT023824 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
