HCSGD entry for GTF2A1
1. General information
| Official gene symbol | GTF2A1 |
|---|---|
| Entrez ID | 2957 |
| Gene full name | general transcription factor IIA, 1, 19/37kDa |
| Other gene symbols | TF2A1 TFIIA TFIIA-42 TFIIAL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003713 | Transcription coactivator activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005672 | Transcription factor TFIIA complex | IDA IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | IEA TAS | biological_process |
| GO:0006368 | Transcription elongation from RNA polymerase II promoter | TAS | biological_process |
| GO:0008134 | Transcription factor binding | IPI | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0017025 | TBP-class protein binding | IPI | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0527823601 | 0.9581844117 | 0.5025707220 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0927576440 |
| GSE13712_SHEAR | Up | 0.0798473252 |
| GSE13712_STATIC | Up | 0.1477936113 |
| GSE19018 | Up | 0.0562587801 |
| GSE19899_A1 | Up | 0.3119821617 |
| GSE19899_A2 | Up | 0.1951236041 |
| PubMed_21979375_A1 | Up | 0.9867641437 |
| PubMed_21979375_A2 | Up | 0.2903734750 |
| GSE35957 | Down | -0.0022973373 |
| GSE36640 | Down | -0.4100261298 |
| GSE54402 | Up | 0.3857343760 |
| GSE9593 | Up | 0.0569790333 |
| GSE43922 | Up | 0.3738835448 |
| GSE24585 | Up | 0.2436885965 |
| GSE37065 | Down | -0.1187217945 |
| GSE28863_A1 | Down | -0.0486636728 |
| GSE28863_A2 | Down | -0.0445398201 |
| GSE28863_A3 | Down | -0.2256018326 |
| GSE28863_A4 | Up | 0.1380545959 |
| GSE48662 | Up | 0.9809815349 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-96-5p | MIMAT0000095 | MIRT027887 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030695 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-424-5p | MIMAT0001341 | MIRT042458 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
