HCSGD entry for DNMT3L
1. General information
| Official gene symbol | DNMT3L |
|---|---|
| Entrez ID | 29947 |
| Gene full name | DNA (cytosine-5-)-methyltransferase 3-like |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000794 | Condensed nuclear chromosome | IEA | cellular_component |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0001890 | Placenta development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005720 | Nuclear heterochromatin | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006306 | DNA methylation | NAS | biological_process |
| GO:0006349 | Regulation of gene expression by genetic imprinting | NAS | biological_process |
| GO:0007283 | Spermatogenesis | NAS | biological_process |
| GO:0008047 | Enzyme activator activity | IDA | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0060718 | Chorionic trophoblast cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4618008130 | 0.8995821929 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0747409927 |
| GSE13712_SHEAR | Up | 0.1897418560 |
| GSE13712_STATIC | Down | -0.1701107752 |
| GSE19018 | Up | 0.0461470386 |
| GSE19899_A1 | Up | 0.2469120545 |
| GSE19899_A2 | Up | 0.0410570921 |
| PubMed_21979375_A1 | Down | -0.4020341624 |
| PubMed_21979375_A2 | Up | 0.0666105968 |
| GSE35957 | Up | 0.0531822374 |
| GSE36640 | Up | 0.0529200660 |
| GSE54402 | Down | -0.1025415194 |
| GSE9593 | Up | 0.0211541278 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1618477743 |
| GSE28863_A2 | Up | 0.0034547298 |
| GSE28863_A3 | Up | 0.2669069438 |
| GSE28863_A4 | Up | 0.1145938056 |
| GSE48662 | Down | -0.0179498729 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
