HCSGD entry for HAL
1. General information
| Official gene symbol | HAL |
|---|---|
| Entrez ID | 3034 |
| Gene full name | histidine ammonia-lyase |
| Other gene symbols | HIS HSTD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004397 | Histidine ammonia-lyase activity | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006548 | Histidine catabolic process | TAS | biological_process |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0016841 | Ammonia-lyase activity | IEA | molecular_function |
| GO:0019556 | Histidine catabolic process to glutamate and formamide | IEA | biological_process |
| GO:0019557 | Histidine catabolic process to glutamate and formate | IEA | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6972125679 | 0.8785589719 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0464269624 |
| GSE13712_SHEAR | Down | -0.0410501867 |
| GSE13712_STATIC | Up | 0.0180124936 |
| GSE19018 | Down | -0.0245999270 |
| GSE19899_A1 | Up | 0.0906185467 |
| GSE19899_A2 | Up | 0.0312965956 |
| PubMed_21979375_A1 | Up | 0.2515377974 |
| PubMed_21979375_A2 | Up | 0.1898635823 |
| GSE35957 | Up | 0.1962121506 |
| GSE36640 | Up | 0.0243884653 |
| GSE54402 | Up | 0.0897346371 |
| GSE9593 | Down | -0.0280271914 |
| GSE43922 | Up | 0.0102069328 |
| GSE24585 | Down | -0.2766987578 |
| GSE37065 | Down | -0.0262498191 |
| GSE28863_A1 | Down | -0.0134752137 |
| GSE28863_A2 | Up | 0.0704171854 |
| GSE28863_A3 | Up | 0.1717575145 |
| GSE28863_A4 | Up | 0.0179927243 |
| GSE48662 | Up | 0.0249392738 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020785 | Reporter assay;Other | Non-Functional MTI | 20584899 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
