HCSGD entry for HAS1

1. General information

Official gene symbolHAS1
Entrez ID3036
Gene full namehyaluronan synthase 1
Other gene symbolsHAS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006024Glycosaminoglycan biosynthetic processTASbiological_process
GO:0007155Cell adhesionTASbiological_process
GO:0010764Negative regulation of fibroblast migrationIMPbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0030212Hyaluronan metabolic processTASbiological_process
GO:0030213Hyaluronan biosynthetic processIEA TASbiological_process
GO:0036120Cellular response to platelet-derived growth factor stimulusIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045226Extracellular polysaccharide biosynthetic processISSbiological_process
GO:0050501Hyaluronan synthase activityIEA ISSmolecular_function
GO:0085029Extracellular matrix assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40804865320.06053025720.99999024730.4629984021

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1386313216
GSE13712_SHEARDown-0.2312545275
GSE13712_STATICDown-0.0873428743
GSE19018Down-0.0736310412
GSE19899_A1Down-0.0496965132
GSE19899_A2Up0.1234265086
PubMed_21979375_A1Down-0.3400534738
PubMed_21979375_A2Down-0.1784377241
GSE35957Down-3.0000011001
GSE36640Up0.0943080512
GSE54402Up0.2668582687
GSE9593Down-1.6618469686
GSE43922Up0.0966992459
GSE24585Up0.0107895578
GSE37065Up0.2823996626
GSE28863_A1Down-0.2102859569
GSE28863_A2Down-0.0937244019
GSE28863_A3Up0.3768130508
GSE28863_A4Up0.2035163541
GSE48662Up0.4445390753

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.