HCSGD entry for HBE1
1. General information
| Official gene symbol | HBE1 |
|---|---|
| Entrez ID | 3046 |
| Gene full name | hemoglobin, epsilon 1 |
| Other gene symbols | HBE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0005344 | Oxygen transporter activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005833 | Hemoglobin complex | IEA | cellular_component |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0019825 | Oxygen binding | IEA | molecular_function |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0031721 | Hemoglobin alpha binding | IEA | molecular_function |
| GO:0051291 | Protein heterooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8624484442 | 0.4103579841 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0688558548 |
| GSE13712_SHEAR | Up | 0.0536422324 |
| GSE13712_STATIC | Up | 0.0236720303 |
| GSE19018 | Up | 0.1260277549 |
| GSE19899_A1 | Down | -0.0408925418 |
| GSE19899_A2 | Down | -0.3352051284 |
| PubMed_21979375_A1 | Up | 0.0100293214 |
| PubMed_21979375_A2 | Down | -0.0719067156 |
| GSE35957 | Up | 0.2984220791 |
| GSE36640 | Down | -1.9731802230 |
| GSE54402 | Down | -0.0241470856 |
| GSE9593 | Up | 0.3681203365 |
| GSE43922 | Up | 0.0102069328 |
| GSE24585 | Down | -0.0502169412 |
| GSE37065 | Down | -0.0150230027 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0001624885 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017542 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
