HCSGD entry for HCRTR2


1. General information

Official gene symbolHCRTR2
Entrez ID3062
Gene full namehypocretin (orexin) receptor 2
Other gene symbolsOX2R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007631Feeding behaviorIEAbiological_process
GO:0008188Neuropeptide receptor activityTASmolecular_function
GO:0016499Orexin receptor activityIEAmolecular_function
GO:0017046Peptide hormone bindingIEAmolecular_function
GO:0022410Circadian sleep/wake cycle processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83177930550.60735502450.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1533616929
GSE13712_SHEARDown-0.1476389973
GSE13712_STATICDown-0.0420862216
GSE19018Down-0.2180664061
GSE19899_A1Up0.1830609346
GSE19899_A2Up0.1053581610
PubMed_21979375_A1Up0.3001185534
PubMed_21979375_A2Up0.0878406360
GSE35957Up0.0015658222
GSE36640Down-0.0915964592
GSE54402Down-0.1742500978
GSE9593Down-0.2103119302
GSE43922Up0.0150353435
GSE24585Up0.1943557494
GSE37065Down-0.0667380452
GSE28863_A1Down-0.1175178569
GSE28863_A2Down-0.0413805456
GSE28863_A3Up0.1459866960
GSE28863_A4Down-0.0885253848
GSE48662Down-0.0104452650

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.