HCSGD entry for HLA-DOB
1. General information
| Official gene symbol | HLA-DOB |
|---|---|
| Entrez ID | 3112 |
| Gene full name | major histocompatibility complex, class II, DO beta |
| Other gene symbols | DOB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002504 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | IEA | biological_process |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0032395 | MHC class II receptor activity | TAS | molecular_function |
| GO:0042613 | MHC class II protein complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2447900992 | 0.9222803731 | 0.9328391776 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0089915613 |
| GSE13712_SHEAR | Down | -0.0297752895 |
| GSE13712_STATIC | Up | 0.0497800985 |
| GSE19018 | Down | -0.0245397807 |
| GSE19899_A1 | Up | 0.0871861502 |
| GSE19899_A2 | Up | 0.1353349718 |
| PubMed_21979375_A1 | Down | -0.0379245960 |
| PubMed_21979375_A2 | Up | 0.1700382640 |
| GSE35957 | Up | 0.3312047051 |
| GSE36640 | Up | 0.6761259443 |
| GSE54402 | Down | -0.0207692699 |
| GSE9593 | Down | -0.1281549788 |
| GSE43922 | Up | 0.0992584486 |
| GSE24585 | Up | 0.3797202687 |
| GSE37065 | Up | 0.3210598741 |
| GSE28863_A1 | Down | -0.1340169550 |
| GSE28863_A2 | Down | -0.0656793292 |
| GSE28863_A3 | Up | 0.0841462485 |
| GSE28863_A4 | Up | 0.0590776464 |
| GSE48662 | Up | 0.2181869280 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
