HCSGD entry for AOC2


1. General information

Official gene symbolAOC2
Entrez ID314
Gene full nameamine oxidase, copper containing 2 (retina-specific)
Other gene symbolsDAO2 RAO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005507Copper ion bindingIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006584Catecholamine metabolic processIEAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0008131Primary amine oxidase activityIEAmolecular_function
GO:0009055Electron carrier activityTASmolecular_function
GO:0009308Amine metabolic processIEAbiological_process
GO:0048038Quinone bindingIEAmolecular_function
GO:0052593Tryptamine:oxygen oxidoreductase (deaminating) activityIEAmolecular_function
GO:0052594Aminoacetone:oxygen oxidoreductase(deaminating) activityIEAmolecular_function
GO:0052595Aliphatic-amine oxidase activityIEAmolecular_function
GO:0052596Phenethylamine:oxygen oxidoreductase (deaminating) activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00868065040.85511003760.23886917451.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1225923167
GSE13712_SHEARUp0.8155457320
GSE13712_STATICUp0.2052017757
GSE19018Up0.1745251867
GSE19899_A1Up0.5022341595
GSE19899_A2Up0.8407691281
PubMed_21979375_A1Up2.6009276346
PubMed_21979375_A2Up1.9654627592
GSE35957Down-0.0646051983
GSE36640Up0.2998670789
GSE54402Up0.4315404951
GSE9593Down-0.6556012350
GSE43922Up0.1307959222
GSE24585Down-0.7770015532
GSE37065Up0.7294923844
GSE28863_A1Down-0.2572603671
GSE28863_A2Up0.1976594126
GSE28863_A3Up0.1430325143
GSE28863_A4Down-0.0631982093
GSE48662Up0.1050074147

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7a-5pMIMAT0000062MIRT052452CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.