HCSGD entry for DNAJB1
1. General information
| Official gene symbol | DNAJB1 |
|---|---|
| Entrez ID | 3337 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| Other gene symbols | HSPF1 Hdj1 Hsp40 RSPH16B Sis1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006986 | Response to unfolded protein | TAS | biological_process |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051085 | Chaperone mediated protein folding requiring cofactor | IEA | biological_process |
| GO:0070389 | Chaperone cofactor-dependent protein refolding | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0189428859 | 0.9824039322 | 0.3364343455 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5223329345 |
| GSE13712_SHEAR | Up | 0.3022636957 |
| GSE13712_STATIC | Up | 0.2508067132 |
| GSE19018 | Down | -0.1982118837 |
| GSE19899_A1 | Up | 0.2106474280 |
| GSE19899_A2 | Up | 0.4564277201 |
| PubMed_21979375_A1 | Up | 0.8684253085 |
| PubMed_21979375_A2 | Down | -0.0844320009 |
| GSE35957 | Up | 0.2208202325 |
| GSE36640 | Up | 0.4753050998 |
| GSE54402 | Up | 0.6627095959 |
| GSE9593 | Up | 0.7271864224 |
| GSE43922 | Up | 0.0508543582 |
| GSE24585 | Up | 0.2306916584 |
| GSE37065 | Up | 0.1242897581 |
| GSE28863_A1 | Up | 0.2036975026 |
| GSE28863_A2 | Up | 0.0310026524 |
| GSE28863_A3 | Down | -0.2543170560 |
| GSE28863_A4 | Up | 0.1513102299 |
| GSE48662 | Up | 0.2395929061 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001371 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT001553 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023313 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028591 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031754 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047590 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
