HCSGD entry for GPIHBP1

1. General information

Official gene symbolGPIHBP1
Entrez ID338328
Gene full nameglycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
Other gene symbolsGPI-HBP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0006869Lipid transportIEAbiological_process
GO:0006886Intracellular protein transportISSbiological_process
GO:0008035High-density lipoprotein particle bindingIEAmolecular_function
GO:0008289Lipid bindingIEAmolecular_function
GO:0008320Protein transmembrane transporter activityISSmolecular_function
GO:0009897External side of plasma membraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneISScellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0017038Protein importISSbiological_process
GO:0031362Anchored component of external side of plasma membraneIDAcellular_component
GO:0034364High-density lipoprotein particleIEAcellular_component
GO:0034394Protein localization to cell surfaceISSbiological_process
GO:0035473Lipase bindingIPImolecular_function
GO:0035478Chylomicron bindingIDAmolecular_function
GO:0042632Cholesterol homeostasisISSbiological_process
GO:0045056TranscytosisISSbiological_process
GO:0050821Protein stabilizationISSbiological_process
GO:0051006Positive regulation of lipoprotein lipase activityIMPbiological_process
GO:0055085Transmembrane transportISSbiological_process
GO:0070328Triglyceride homeostasisIMPbiological_process
GO:0071503Response to heparinIMPbiological_process
GO:0071806Protein transmembrane transportISSbiological_process
GO:0071813Lipoprotein particle bindingIDAmolecular_function
GO:0090321Positive regulation of chylomicron remnant clearanceISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58232327800.85018371640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0356213311
GSE13712_SHEARDown-0.0284403215
GSE13712_STATICDown-0.0995585386
GSE19018Up0.1650476044
GSE19899_A1Up0.0488797620
GSE19899_A2Up0.0542601601
PubMed_21979375_A1Down-0.0612846538
PubMed_21979375_A2Down-0.3528651401
GSE35957Down-0.0647651651
GSE36640Up0.0041494786
GSE54402Up0.0573408934
GSE9593Up0.0999635652
GSE43922Up0.1770142314
GSE24585Up0.0840088275
GSE37065Down-0.0410710742
GSE28863_A1Down-0.0162074535
GSE28863_A2Up0.1580792007
GSE28863_A3Up0.1878018964
GSE28863_A4Up0.0848750599
GSE48662Up0.0931331213

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017452MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

20713685VAT-EC exhibited a marked angiogenic and inflammatory state with decreased expression of metabolism-related genes, including endothelial lipase, GPIHBP1, and PPAR gamma
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