HCSGD entry for ABCB5

1. General information

Official gene symbolABCB5
Entrez ID340273
Gene full nameATP-binding cassette, sub-family B (MDR/TAP), member 5
Other gene symbolsABCB5alpha ABCB5beta EST422562
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIBAcellular_component
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0006200ATP catabolic processIBAbiological_process
GO:0008152Metabolic processIBAbiological_process
GO:0015562Efflux transmembrane transporter activityIDAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIBAcellular_component
GO:0042391Regulation of membrane potentialIDAbiological_process
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIBA IEAmolecular_function
GO:0046581Intercellular canaliculusIBAcellular_component
GO:0055085Transmembrane transportIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55941605940.93814003650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0425012940
GSE13712_SHEARDown-0.0772337397
GSE13712_STATICDown-0.0204575251
GSE19018Up0.2082044910
GSE19899_A1Up0.0776027255
GSE19899_A2Up0.0478703029
PubMed_21979375_A1Up0.1309216782
PubMed_21979375_A2Up0.0126163941
GSE35957Up0.0840469210
GSE36640Up0.0326251715
GSE54402Down-0.0068127754
GSE9593Down-0.0822886281
GSE43922Up0.1215853527
GSE24585Up0.2595970080
GSE37065Up0.0753414983
GSE28863_A1Up0.0257451405
GSE28863_A2Up0.0806630282
GSE28863_A3Up0.1597075747
GSE28863_A4Down-0.0682991858
GSE48662Up0.0591402216

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Biricodar dicitrateDB04851 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023509MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.