HCSGD entry for IFNA21
1. General information
| Official gene symbol | IFNA21 |
|---|---|
| Entrez ID | 3452 |
| Gene full name | interferon, alpha 21 |
| Other gene symbols | IFN-alphaI LeIF F leIF-F |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002250 | Adaptive immune response | IBA | biological_process |
| GO:0002286 | T cell activation involved in immune response | IBA | biological_process |
| GO:0002323 | Natural killer cell activation involved in immune response | IBA | biological_process |
| GO:0005125 | Cytokine activity | IBA | molecular_function |
| GO:0005126 | Cytokine receptor binding | TAS | molecular_function |
| GO:0005132 | Type I interferon receptor binding | IBA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IBA | cellular_component |
| GO:0006959 | Humoral immune response | IBA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | IBA TAS | biological_process |
| GO:0030183 | B cell differentiation | IBA | biological_process |
| GO:0033141 | Positive regulation of peptidyl-serine phosphorylation of STAT protein | IBA | biological_process |
| GO:0042100 | B cell proliferation | IBA | biological_process |
| GO:0043330 | Response to exogenous dsRNA | IBA | biological_process |
| GO:0045087 | Innate immune response | IBA TAS | biological_process |
| GO:0045343 | Regulation of MHC class I biosynthetic process | IBA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
| GO:0060337 | Type I interferon signaling pathway | TAS | biological_process |
| GO:0060338 | Regulation of type I interferon-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3720810987 | 0.9549286121 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0654931903 |
| GSE13712_SHEAR | Up | 0.0974783867 |
| GSE13712_STATIC | Down | -0.0155306810 |
| GSE19018 | Up | 0.1533688423 |
| GSE19899_A1 | Up | 0.1153802791 |
| GSE19899_A2 | Up | 0.3742975887 |
| PubMed_21979375_A1 | Down | -0.0007521728 |
| PubMed_21979375_A2 | Up | 0.0871834048 |
| GSE35957 | Up | 0.1870772889 |
| GSE36640 | Up | 0.2533104595 |
| GSE54402 | Up | 0.2607396442 |
| GSE9593 | Down | -0.2505711191 |
| GSE43922 | Up | 0.0113788423 |
| GSE24585 | Up | 0.2305376692 |
| GSE37065 | Down | -0.0445035350 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0249497565 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016701 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
