HCSGD entry for IL13

1. General information

Official gene symbolIL13
Entrez ID3596
Gene full nameinterleukin 13
Other gene symbolsIL-13 P600
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002639Positive regulation of immunoglobulin productionIEAbiological_process
GO:0005125Cytokine activityIEAmolecular_function
GO:0005144Interleukin-13 receptor bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDAcellular_component
GO:0005615Extracellular spaceISScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0006954Inflammatory responseTASbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionNASbiological_process
GO:0007267Cell-cell signalingICbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0010155Regulation of proton transportIEAbiological_process
GO:0030890Positive regulation of B cell proliferationIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0032723Positive regulation of connective tissue growth factor productionIEAbiological_process
GO:0035094Response to nicotineIEAbiological_process
GO:0042526Positive regulation of tyrosine phosphorylation of Stat6 proteinIEAbiological_process
GO:0043032Positive regulation of macrophage activationIEAbiological_process
GO:0045471Response to ethanolIEAbiological_process
GO:0048661Positive regulation of smooth muscle cell proliferationIEAbiological_process
GO:0050714Positive regulation of protein secretionIEAbiological_process
GO:0051281Positive regulation of release of sequestered calcium ion into cytosolIEAbiological_process
GO:0071260Cellular response to mechanical stimulusIEAbiological_process
GO:0071345Cellular response to cytokine stimulusIEAbiological_process
GO:0071635Negative regulation of transforming growth factor beta productionIEAbiological_process
GO:1901247Negative regulation of lung ciliated cell differentiationNASbiological_process
GO:1901251Positive regulation of lung goblet cell differentiationNASbiological_process
GO:2000231Positive regulation of pancreatic stellate cell proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.29492909080.83646246340.99419979511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1667876604
GSE13712_SHEARDown-0.2028523797
GSE13712_STATICUp0.3217733152
GSE19018Up0.1212767775
GSE19899_A1Down-0.0360887507
GSE19899_A2Up0.1316516355
PubMed_21979375_A1Up0.1181169800
PubMed_21979375_A2Up0.0373614262
GSE35957Up0.1571587703
GSE36640Down-0.0892223408
GSE54402Up0.0397911991
GSE9593Up0.0778252721
GSE43922Up0.0508278047
GSE24585Up0.0497445509
GSE37065Up0.0246207582
GSE28863_A1Up0.0453583043
GSE28863_A2Up0.2887718904
GSE28863_A3Up0.3338501815
GSE28863_A4Down-0.0172044171
GSE48662Up0.0165436563

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Cintredekin BesudotoxDB05305 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7d-5pMIMAT0000065MIRT006398Luciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
hsa-let-7g-5pMIMAT0000414MIRT006399Luciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
hsa-let-7i-5pMIMAT0000415MIRT006401Luciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
hsa-let-7f-5pMIMAT0000067MIRT006400Luciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
hsa-miR-98-5pMIMAT0000096MIRT006397Luciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.