HCSGD entry for IDO1

1. General information

Official gene symbolIDO1
Entrez ID3620
Gene full nameindoleamine 2,3-dioxygenase 1
Other gene symbolsIDO IDO-1 INDO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002534Cytokine production involved in inflammatory responseIEAbiological_process
GO:0002666Positive regulation of T cell tolerance inductionIEAbiological_process
GO:0002678Positive regulation of chronic inflammatory responseIEAbiological_process
GO:0002830Positive regulation of type 2 immune responseIEAbiological_process
GO:0004833Tryptophan 2,3-dioxygenase activityEXP IEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006569Tryptophan catabolic processTASbiological_process
GO:0007565Female pregnancyTASbiological_process
GO:0009055Electron carrier activityTASmolecular_function
GO:0019441Tryptophan catabolic process to kynurenineIEAbiological_process
GO:0020037Heme bindingIEAmolecular_function
GO:0030485Smooth muscle contractile fiberIEAcellular_component
GO:0032421Stereocilium bundleIEAcellular_component
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0032693Negative regulation of interleukin-10 productionIEAbiological_process
GO:0032735Positive regulation of interleukin-12 productionIEAbiological_process
GO:0033555Multicellular organismal response to stressIEAbiological_process
GO:0033754Indoleamine 2,3-dioxygenase activityIEAmolecular_function
GO:0034276Kynurenic acid biosynthetic processIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0036269Swimming behaviorIEAbiological_process
GO:0043065Positive regulation of apoptotic processIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046007Negative regulation of activated T cell proliferationIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0070233Negative regulation of T cell apoptotic processIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06473344100.35308462440.54856693501.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2259840230
GSE13712_SHEARUp0.5995298556
GSE13712_STATICUp2.0383361177
GSE19018Up0.2602995581
GSE19899_A1Up0.0461080732
GSE19899_A2Down-0.0705308932
PubMed_21979375_A1Up0.1015731467
PubMed_21979375_A2Down-0.0447706314
GSE35957Down-0.1280290017
GSE36640Up0.3653130176
GSE54402Up0.0451404418
GSE9593Down-0.2672414194
GSE43922Up0.0171987162
GSE24585Down-0.3148936992
GSE37065Up2.1323437944
GSE28863_A1Down-0.4950395745
GSE28863_A2Up0.2633938915
GSE28863_A3Down-0.0194755941
GSE28863_A4Down-0.3086227532
GSE48662Up0.7991856355

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.