HCSGD entry for ITIH1
1. General information
| Official gene symbol | ITIH1 |
|---|---|
| Entrez ID | 3697 |
| Gene full name | inter-alpha-trypsin inhibitor heavy chain 1 |
| Other gene symbols | H1P IATIH IGHEP1 ITI-HC1 ITIH SHAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | TAS | molecular_function |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0030212 | Hyaluronan metabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7251562403 | 0.7632336461 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0760262377 |
| GSE13712_SHEAR | Down | -0.1257061874 |
| GSE13712_STATIC | Up | 0.0653222887 |
| GSE19018 | Down | -0.0416328171 |
| GSE19899_A1 | Down | -0.0123217443 |
| GSE19899_A2 | Down | -0.1025310980 |
| PubMed_21979375_A1 | Down | -0.0568080234 |
| PubMed_21979375_A2 | Down | -0.1710534854 |
| GSE35957 | Up | 0.1268086901 |
| GSE36640 | Up | 0.1523473741 |
| GSE54402 | Up | 0.0176879737 |
| GSE9593 | Down | -0.0660919906 |
| GSE43922 | Up | 0.1347669357 |
| GSE24585 | Up | 0.0515938962 |
| GSE37065 | Down | -0.0420198765 |
| GSE28863_A1 | Up | 0.0326480167 |
| GSE28863_A2 | Up | 0.1094714743 |
| GSE28863_A3 | Up | 0.1982925246 |
| GSE28863_A4 | Up | 0.1038572855 |
| GSE48662 | Up | 0.0683997992 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018625 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
