HCSGD entry for STT3A
1. General information
| Official gene symbol | STT3A |
|---|---|
| Entrez ID | 3703 |
| Gene full name | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| Other gene symbols | ITM1 STT3-A TMC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004576 | Oligosaccharyl transferase activity | IEA | molecular_function |
| GO:0004579 | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | IMP ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006486 | Protein glycosylation | IEA | biological_process |
| GO:0008250 | Oligosaccharyltransferase complex | ISS TAS | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | IMP ISS TAS | biological_process |
| GO:0043686 | Co-translational protein modification | IMP | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4676489647 | 0.1299491623 | 0.9999902473 | 0.6940718807 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0183611102 |
| GSE13712_SHEAR | Down | -0.2120602152 |
| GSE13712_STATIC | Down | -0.3074556809 |
| GSE19018 | Up | 0.5326647785 |
| GSE19899_A1 | Up | 0.2315259031 |
| GSE19899_A2 | Down | -0.3846117484 |
| PubMed_21979375_A1 | Down | -0.5374684088 |
| PubMed_21979375_A2 | Down | -0.1364514303 |
| GSE35957 | Down | -0.5862035638 |
| GSE36640 | Down | -0.2370972031 |
| GSE54402 | Up | 0.0910581339 |
| GSE9593 | Up | 0.1947536193 |
| GSE43922 | Up | 0.0530169597 |
| GSE24585 | Down | -0.2386349390 |
| GSE37065 | Down | -0.1336203224 |
| GSE28863_A1 | Up | 0.2305961639 |
| GSE28863_A2 | Up | 0.2367315894 |
| GSE28863_A3 | Down | -0.4196375263 |
| GSE28863_A4 | Up | 0.2075981042 |
| GSE48662 | Down | -0.3439410384 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022920 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-484 | MIMAT0002174 | MIRT042092 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043817 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047423 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047614 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
