HCSGD entry for KCNA4
1. General information
| Official gene symbol | KCNA4 |
|---|---|
| Entrez ID | 3739 |
| Gene full name | potassium voltage-gated channel, shaker-related subfamily, member 4 |
| Other gene symbols | HBK4 HK1 HPCN2 HUKII KCNA4L KCNA8 KV1.4 PCN2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005249 | Voltage-gated potassium channel activity | TAS | molecular_function |
| GO:0005251 | Delayed rectifier potassium channel activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0008076 | Voltage-gated potassium channel complex | IEA | cellular_component |
| GO:0030955 | Potassium ion binding | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0605756658 | 0.9250996011 | 0.5330699097 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0631996520 |
| GSE13712_SHEAR | Down | -0.0435337669 |
| GSE13712_STATIC | Down | -0.0638882539 |
| GSE19018 | Up | 0.2451419721 |
| GSE19899_A1 | Up | 0.0549337852 |
| GSE19899_A2 | Down | -0.0678684484 |
| PubMed_21979375_A1 | Up | 0.3030766775 |
| PubMed_21979375_A2 | Down | -0.1099910201 |
| GSE35957 | Up | 0.6205094794 |
| GSE36640 | Down | -0.0058324465 |
| GSE54402 | Up | 0.0019760104 |
| GSE9593 | Up | 0.0605544569 |
| GSE43922 | Up | 0.0546631074 |
| GSE24585 | Up | 0.0128478695 |
| GSE37065 | Up | 0.0623645055 |
| GSE28863_A1 | Up | 1.1837604762 |
| GSE28863_A2 | Down | -0.0206156781 |
| GSE28863_A3 | Up | 0.9537661636 |
| GSE28863_A4 | Up | 0.0626972837 |
| GSE48662 | Up | 0.0101095372 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017281 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
