HCSGD entry for KCND2

1. General information

Official gene symbolKCND2
Entrez ID3751
Gene full namepotassium voltage-gated channel, Shal-related subfamily, member 2
Other gene symbolsKV4.2 RK5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001508Action potentialTASbiological_process
GO:0005249Voltage-gated potassium channel activityIEA NASmolecular_function
GO:0005250A-type (transient outward) potassium channel activityIBAmolecular_function
GO:0005251Delayed rectifier potassium channel activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0008076Voltage-gated potassium channel complexIEAcellular_component
GO:0043197Dendritic spineNAScellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051260Protein homooligomerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00157807070.84184543900.10666538461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5751839054
GSE13712_SHEARDown-0.0512790444
GSE13712_STATICUp0.0664695112
GSE19018Up0.0083151500
GSE19899_A1Up0.1169998361
GSE19899_A2Up0.2093373577
PubMed_21979375_A1Down-0.4120565554
PubMed_21979375_A2Up0.5950606046
GSE35957Up4.2730291138
GSE36640Up1.3031545334
GSE54402Up0.4744343648
GSE9593Up0.2509229270
GSE43922Up0.3174041441
GSE24585Down-0.0660395251
GSE37065Up0.3980555944
GSE28863_A1Up0.8899048221
GSE28863_A2Up1.0336765327
GSE28863_A3Up0.8801908550
GSE28863_A4Down-0.1888612975
GSE48662Up0.1667497569

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DisopyramideDB00280 APRD00507
DalfampridineDB06637 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.