HCSGD entry for SLC27A1


1. General information

Official gene symbolSLC27A1
Entrez ID376497
Gene full namesolute carrier family 27 (fatty acid transporter), member 1
Other gene symbolsACSVL5 FATP FATP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0001579Medium-chain fatty acid transportIEAbiological_process
GO:0003824Catalytic activityIEAmolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006631Fatty acid metabolic processIEAbiological_process
GO:0006646Phosphatidylethanolamine biosynthetic processIMPbiological_process
GO:0006654Phosphatidic acid biosynthetic processIMPbiological_process
GO:0006655Phosphatidylglycerol biosynthetic processIMPbiological_process
GO:0006656Phosphatidylcholine biosynthetic processIMPbiological_process
GO:0006659Phosphatidylserine biosynthetic processIMPbiological_process
GO:0006661Phosphatidylinositol biosynthetic processIMPbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0015245Fatty acid transporter activityIEAmolecular_function
GO:0015909Long-chain fatty acid transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0031652Positive regulation of heat generationIEAbiological_process
GO:0031957Very long-chain fatty acid-CoA ligase activityIEAmolecular_function
GO:0032049Cardiolipin biosynthetic processIMPbiological_process
GO:0032868Response to insulinIEAbiological_process
GO:0033211Adiponectin-activated signaling pathwayIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0071072Negative regulation of phospholipid biosynthetic processIMPbiological_process
GO:0071902Positive regulation of protein serine/threonine kinase activityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02437248200.41836517610.36969919351.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3742377395
GSE13712_SHEARDown-0.9879097313
GSE13712_STATICDown-0.6471328304
GSE19018Up1.1383258828
GSE19899_A1Down-0.2025704581
GSE19899_A2Down-0.0616317334
PubMed_21979375_A1Up0.3891608883
PubMed_21979375_A2Up0.6310953508
GSE35957Up1.1020306465
GSE36640Up0.2134230046
GSE54402Down-0.0626079695
GSE9593Up1.1740983784
GSE43922Up0.0557475460
GSE24585Up0.0478493486
GSE37065Down-0.1548857748
GSE28863_A1Up0.4604621102
GSE28863_A2Up0.4470214799
GSE28863_A3Up0.3723576308
GSE28863_A4Down-0.2044557315
GSE48662Up0.5146903065

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017877MicroarrayFunctional MTI (Weak)18185580
hsa-miR-30d-5pMIMAT0000245MIRT047803CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.