HCSGD entry for PLEKHM3


1. General information

Official gene symbolPLEKHM3
Entrez ID389072
Gene full namepleckstrin homology domain containing, family M, member 3
Other gene symbolsDAPR PLEKHM1L
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0035556Intracellular signal transductionIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04115471680.94911681930.45460448071.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0060988919
GSE13712_SHEARUp0.2832936102
GSE13712_STATICUp0.4913016035
GSE19018Up0.3588198489
GSE19899_A1Down-0.0285045705
GSE19899_A2Up0.2369787887
PubMed_21979375_A1Down-0.0804795098
PubMed_21979375_A2Up0.3935065983
GSE35957Up0.2246444918
GSE36640Up0.5537412731
GSE54402Down-0.0769632470
GSE9593Up0.1222604107
GSE43922Down-0.0864272133
GSE24585Up0.4164688373
GSE37065Up0.1842670596
GSE28863_A1Up0.5597635043
GSE28863_A2Up0.5345242053
GSE28863_A3Down-0.1421452354
GSE28863_A4Down-0.2045738279
GSE48662Up0.2768501703

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT045219CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050484CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.