HCSGD entry for LIPE


1. General information

Official gene symbolLIPE
Entrez ID3991
Gene full namelipase, hormone-sensitive
Other gene symbolsHSL LHS
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004806Triglyceride lipase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005811Lipid particleIEA ISScellular_component
GO:0005829CytosolIEAcellular_component
GO:0005901CaveolaIEAcellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0008203Cholesterol metabolic processIEAbiological_process
GO:0016042Lipid catabolic processIEA ISSbiological_process
GO:0016298Lipase activityIEAmolecular_function
GO:0016787Hydrolase activityIEAmolecular_function
GO:0019433Triglyceride catabolic processIEA TASbiological_process
GO:0019901Protein kinase bindingIEAmolecular_function
GO:0033878Hormone-sensitive lipase activityIEAmolecular_function
GO:0042758Long-chain fatty acid catabolic processIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046340Diacylglycerol catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88848780440.26683315220.99999024730.9890025176

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0705321664
GSE13712_SHEARDown-0.5594411907
GSE13712_STATICDown-0.2935938038
GSE19018Up0.1098735512
GSE19899_A1Down-0.0066685131
GSE19899_A2Up0.2484859975
PubMed_21979375_A1Down-0.0034144747
PubMed_21979375_A2Down-0.1689437848
GSE35957Down-0.0544337575
GSE36640Down-0.1320362841
GSE54402Up0.0077763090
GSE9593Down-0.7338610695
GSE43922Up0.0665596676
GSE24585Down-0.0624921320
GSE37065Down-0.1641514612
GSE28863_A1Down-0.0998045889
GSE28863_A2Up0.0051573846
GSE28863_A3Up0.3180974363
GSE28863_A4Up0.0669426259
GSE48662Down-0.1009469948

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.