HCSGD entry for LMAN1

1. General information

Official gene symbolLMAN1
Entrez ID3998
Gene full namelectin, mannose-binding, 1
Other gene symbolsERGIC-53 ERGIC53 F5F8D FMFD1 MCFD1 MR60 gp58
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005537Mannose bindingTASmolecular_function
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005793Endoplasmic reticulum-Golgi intermediate compartmentIDAcellular_component
GO:0006457Protein foldingTASbiological_process
GO:0006888ER to Golgi vesicle-mediated transportTASbiological_process
GO:0007029Endoplasmic reticulum organizationIEAbiological_process
GO:0007030Golgi organizationIMPbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010638Positive regulation of organelle organizationIMPbiological_process
GO:0012507ER to Golgi transport vesicle membraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030017SarcomereIEAcellular_component
GO:0032527Protein exit from endoplasmic reticulumIMPbiological_process
GO:0033116Endoplasmic reticulum-Golgi intermediate compartment membraneIEAcellular_component
GO:0034498Early endosome to Golgi transportIMPbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051082Unfolded protein bindingTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41737771740.06899435050.99999024730.4953628751

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3970950049
GSE13712_SHEARDown-0.1892870726
GSE13712_STATICUp0.0125626863
GSE19018Up0.5449752914
GSE19899_A1Down-0.6386933893
GSE19899_A2Down-0.6853859863
PubMed_21979375_A1Down-1.1109557746
PubMed_21979375_A2Down-1.4787109373
GSE35957Up0.1838679269
GSE36640Down-0.0730343217
GSE54402Down-0.1403617754
GSE9593Up0.2623373827
GSE43922Down-0.0259785389
GSE24585Down-0.2328378081
GSE37065Down-0.0782808204
GSE28863_A1Up0.3060101858
GSE28863_A2Up0.3437432943
GSE28863_A3Down-0.0497124074
GSE28863_A4Up0.2262578174
GSE48662Up0.3218718949

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024823MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026376MicroarrayFunctional MTI (Weak)19074876
hsa-miR-18a-3pMIMAT0002891MIRT040889CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23466301These genes, PDIA3, WDR1, FSTL1, COPG1, LMAN1, and PDIA6, significantly downregulated
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