HCSGD entry for LYL1
1. General information
| Official gene symbol | LYL1 |
|---|---|
| Entrez ID | 4066 |
| Gene full name | lymphoblastic leukemia derived sequence 1 |
| Other gene symbols | bHLHa18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001955 | Blood vessel maturation | IMP | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0030183 | B cell differentiation | IEA ISS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
| GO:0060216 | Definitive hemopoiesis | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4508759242 | 0.4537755594 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0439817995 |
| GSE13712_SHEAR | Down | -0.1916365723 |
| GSE13712_STATIC | Up | 0.4451550606 |
| GSE19018 | Up | 0.1345760129 |
| GSE19899_A1 | Down | -0.0256275126 |
| GSE19899_A2 | Down | -0.0115642040 |
| PubMed_21979375_A1 | Up | 0.0332081558 |
| PubMed_21979375_A2 | Down | -0.3883118381 |
| GSE35957 | Up | 0.4330531396 |
| GSE36640 | Down | -0.1777858869 |
| GSE54402 | Up | 0.0066669361 |
| GSE9593 | Down | -0.1501382958 |
| GSE43922 | Up | 0.0841041890 |
| GSE24585 | Up | 0.1101695326 |
| GSE37065 | Down | -0.1266746996 |
| GSE28863_A1 | Down | -0.3612586846 |
| GSE28863_A2 | Down | -0.0627861713 |
| GSE28863_A3 | Up | 0.3745066677 |
| GSE28863_A4 | Up | 0.1423840956 |
| GSE48662 | Up | 0.1243243406 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017738 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
