HCSGD entry for MIRLET7C

1. General information

Official gene symbolMIRLET7C
Entrez ID406885
Gene full namemicroRNA let-7c
Other gene symbolsLET7C MIRNLET7C hsa-let-7c let-7c
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

Not in the Gene Ontology

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15480091940.99521674330.78221161231.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1733541647
GSE24585Up0.1113994160
GSE37065Up0.1954244331
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

26990999Interestingly, several microRNAs previously associated with senescence and aging, including miR-20a, miR-34a, miR-130a, miR-106b, miR-125, and let-7c, were found elevated
22334139However, no significant correlation was observed between the let-7a and let-7c microRNA expression levels and either the severity of lens opacity or the patient age
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