HCSGD entry for MAGEA1


1. General information

Official gene symbolMAGEA1
Entrez ID4100
Gene full namemelanoma antigen family A, 1 (directs expression of antigen MZ2-E)
Other gene symbolsCT1.1 MAGE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0042826Histone deacetylase bindingIDAmolecular_function
GO:0045746Negative regulation of Notch signaling pathwayIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63887424110.85114703850.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1263632916
GSE13712_SHEARUp0.0623987786
GSE13712_STATICDown-0.3007237358
GSE19018Up0.1061140744
GSE19899_A1Down-0.0016116662
GSE19899_A2Up0.1977258832
PubMed_21979375_A1Up0.1831910134
PubMed_21979375_A2Up0.1577777053
GSE35957Up0.1695695257
GSE36640Down-0.1450480989
GSE54402Up0.1254412627
GSE9593Up0.1250308641
GSE43922Up0.0203023649
GSE24585Down-0.1025560123
GSE37065Down-0.0917338285
GSE28863_A1Down-0.0770451282
GSE28863_A2Up0.0184113549
GSE28863_A3Up0.1539018438
GSE28863_A4Down-0.0684424112
GSE48662Up0.0447975992

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.