HCSGD entry for PIM3
1. General information
| Official gene symbol | PIM3 |
|---|---|
| Entrez ID | 415116 |
| Gene full name | pim-3 oncogene |
| Other gene symbols | pim-3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0007346 | Regulation of mitotic cell cycle | IMP | biological_process |
| GO:0016572 | Histone phosphorylation | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IMP | biological_process |
| GO:0046777 | Protein autophosphorylation | IEA | biological_process |
| GO:0061179 | Negative regulation of insulin secretion involved in cellular response to glucose stimulus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2197310664 | 0.2017512974 | 0.9014247818 | 0.8686890070 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0833588178 |
| GSE13712_SHEAR | Down | -0.4875361333 |
| GSE13712_STATIC | Down | -1.1424384139 |
| GSE19018 | Up | 0.4059255956 |
| GSE19899_A1 | Up | 0.4296908310 |
| GSE19899_A2 | Up | 0.9960699824 |
| PubMed_21979375_A1 | Down | -0.1265886782 |
| PubMed_21979375_A2 | Up | 0.0044080508 |
| GSE35957 | Down | -0.5422617164 |
| GSE36640 | Down | -1.0408462008 |
| GSE54402 | Up | 0.8731493851 |
| GSE9593 | Down | -0.2445199524 |
| GSE43922 | Up | 0.0489784271 |
| GSE24585 | Down | -0.0710578042 |
| GSE37065 | Up | 0.0493127298 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0922999219 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-340-5p | MIMAT0004692 | MIRT019570 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028210 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-940 | MIMAT0004983 | MIRT036626 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037665 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039901 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-151a-3p | MIMAT0000757 | MIRT043598 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
