HCSGD entry for MDFI

1. General information

Official gene symbolMDFI
Entrez ID4188
Gene full nameMyoD family inhibitor
Other gene symbolsI-MF I-mfa
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEA ISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0007257Activation of JUN kinase activityIEAbiological_process
GO:0008134Transcription factor bindingIEAmolecular_function
GO:0009790Embryo developmentTASbiological_process
GO:0009950Dorsal/ventral axis specificationIEA ISSbiological_process
GO:0030178Negative regulation of Wnt signaling pathwayIEA ISSbiological_process
GO:0042994Cytoplasmic sequestering of transcription factorTASbiological_process
GO:0043392Negative regulation of DNA bindingIEA ISSbiological_process
GO:0048704Embryonic skeletal system morphogenesisIEAbiological_process
GO:0060707Trophoblast giant cell differentiationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.50469860570.24176959080.99999024730.9472487943

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1725751884
GSE13712_SHEARDown-0.3816552610
GSE13712_STATICDown-0.6464682290
GSE19018Up0.0927606825
GSE19899_A1Down0.0000000000
GSE19899_A2Up0.0783171838
PubMed_21979375_A1Up0.3450065566
PubMed_21979375_A2Down-0.1634937402
GSE35957Down-0.0295132573
GSE36640Up0.2330146370
GSE54402Up0.0192196462
GSE9593Down-0.2556467086
GSE43922Up0.0593142637
GSE24585Up0.0622964892
GSE37065Down-0.0709797425
GSE28863_A1Down-0.3625224065
GSE28863_A2Down-0.2434075002
GSE28863_A3Up0.3292676839
GSE28863_A4Up0.0532098580
GSE48662Up0.9109699190

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018708MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.