HCSGD entry for DNAJB9
1. General information
| Official gene symbol | DNAJB9 |
|---|---|
| Entrez ID | 4189 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| Other gene symbols | ERdj4 MDG-1 MDG1 MST049 MSTP049 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005730 | Nucleolus | ISS | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006987 | Activation of signaling protein activity involved in unfolded protein response | TAS | biological_process |
| GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0030968 | Endoplasmic reticulum unfolded protein response | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051787 | Misfolded protein binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0007566924 | 0.9918507921 | 0.0773316602 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6182099585 |
| GSE13712_SHEAR | Down | -0.1266507297 |
| GSE13712_STATIC | Up | 0.0994547604 |
| GSE19018 | Down | -0.5248589881 |
| GSE19899_A1 | Up | 1.0527884440 |
| GSE19899_A2 | Up | 0.9493755487 |
| PubMed_21979375_A1 | Up | 1.3595468746 |
| PubMed_21979375_A2 | Up | 0.7323045864 |
| GSE35957 | Up | 0.8377492356 |
| GSE36640 | Up | 2.2434252328 |
| GSE54402 | Up | 0.3877134826 |
| GSE9593 | Up | 1.0049937034 |
| GSE43922 | Up | 0.9082069295 |
| GSE24585 | Up | 0.3622599120 |
| GSE37065 | Up | 0.5641542905 |
| GSE28863_A1 | Up | 0.0753933930 |
| GSE28863_A2 | Up | 0.8661161870 |
| GSE28863_A3 | Down | -0.1199606733 |
| GSE28863_A4 | Down | -0.0142248235 |
| GSE48662 | Up | 0.2933546439 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017907 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024579 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026471 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028383 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037350 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT040986 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044516 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23634235 | Amongst the genes were IRAK3, SelS, HSPA5, HERPUD1, DNAJB9, SEPR1, C18orf55, ARF4, RINT1, NXT1, CADPS2, COG6, and GLRX5 |
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