HCSGD entry for LHX8
1. General information
| Official gene symbol | LHX8 |
|---|---|
| Entrez ID | 431707 |
| Gene full name | LIM homeobox 8 |
| Other gene symbols | LHX7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007611 | Learning or memory | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008585 | Female gonad development | IEA | biological_process |
| GO:0021884 | Forebrain neuron development | IEA | biological_process |
| GO:0042475 | Odontogenesis of dentin-containing tooth | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2201669617 | 0.9414843395 | 0.9019175229 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0704626064 |
| GSE13712_SHEAR | Up | 0.1235708461 |
| GSE13712_STATIC | Up | 0.0927443920 |
| GSE19018 | Down | -0.0203031824 |
| GSE19899_A1 | Down | -0.0428177611 |
| GSE19899_A2 | Up | 0.0709313530 |
| PubMed_21979375_A1 | Up | 0.4173560926 |
| PubMed_21979375_A2 | Down | -0.0355218714 |
| GSE35957 | Up | 0.2539973982 |
| GSE36640 | Up | 0.0684164190 |
| GSE54402 | Down | -0.0285292559 |
| GSE9593 | Up | 0.0238521802 |
| GSE43922 | Up | 0.0137500677 |
| GSE24585 | Up | 0.5932202288 |
| GSE37065 | Down | -0.0212672544 |
| GSE28863_A1 | Down | -0.1561817134 |
| GSE28863_A2 | Up | 0.4084625360 |
| GSE28863_A3 | Up | 0.1340824521 |
| GSE28863_A4 | Up | 0.1576378802 |
| GSE48662 | Up | 0.0383445785 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
