HCSGD entry for ASPA
1. General information
| Official gene symbol | ASPA |
|---|---|
| Entrez ID | 443 |
| Gene full name | aspartoacylase |
| Other gene symbols | ACY2 ASP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004046 | Aminoacylase activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006533 | Aspartate catabolic process | TAS | biological_process |
| GO:0016788 | Hydrolase activity, acting on ester bonds | IEA | molecular_function |
| GO:0019807 | Aspartoacylase activity | IEA | molecular_function |
| GO:0022010 | Central nervous system myelination | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048714 | Positive regulation of oligodendrocyte differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1302688956 | 0.9276912351 | 0.7333126176 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0189082195 |
| GSE13712_SHEAR | Up | 0.1062193353 |
| GSE13712_STATIC | Up | 0.1099866183 |
| GSE19018 | Down | -0.0376942947 |
| GSE19899_A1 | Down | -0.0199918620 |
| GSE19899_A2 | Up | 0.0134594054 |
| PubMed_21979375_A1 | Up | 0.0030339505 |
| PubMed_21979375_A2 | Down | -0.0703895447 |
| GSE35957 | Down | -0.0423332031 |
| GSE36640 | Up | 0.1348141956 |
| GSE54402 | Down | -0.1612618589 |
| GSE9593 | Up | 0.7921993852 |
| GSE43922 | Up | 0.0727775534 |
| GSE24585 | Down | -0.0398844093 |
| GSE37065 | Up | 0.6313525918 |
| GSE28863_A1 | Up | 0.7928990942 |
| GSE28863_A2 | Up | 0.5186993135 |
| GSE28863_A3 | Up | 0.0644981202 |
| GSE28863_A4 | Down | -0.0149560870 |
| GSE48662 | Up | 0.2768965534 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Aspartic Acid | DB00128 | NUTR00016 | EXPT01823 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT052301 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
