HCSGD entry for COX1
1. General information
| Official gene symbol | COX1 |
|---|---|
| Entrez ID | 4512 |
| Gene full name | cytochrome c oxidase subunit I |
| Other gene symbols | COI MTCO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
Not in the Gene Ontology4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2616341552 | 0.7899005205 | 0.9548629280 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2867562207 |
| GSE13712_SHEAR | Down | -0.2023833414 |
| GSE13712_STATIC | Up | 0.0426510967 |
| GSE19018 | Down | -0.8586176442 |
| GSE19899_A1 | Up | 0.1550363466 |
| GSE19899_A2 | Up | 0.5158304989 |
| PubMed_21979375_A1 | Up | 0.1285843877 |
| PubMed_21979375_A2 | Up | 0.1617985243 |
| GSE35957 | Up | 0.3199657076 |
| GSE36640 | Up | 0.2635513086 |
| GSE54402 | Down | -0.0579107707 |
| GSE9593 | Up | 0.1902767898 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035986 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036706 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037444 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-708-5p | MIMAT0004926 | MIRT037747 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-550a-5p | MIMAT0004800 | MIRT037786 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038031 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99b-3p | MIMAT0004678 | MIRT038518 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039016 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039899 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040673 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041193 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-146b-5p | MIMAT0002809 | MIRT041609 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043967 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044069 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044552 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044969 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045588 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046297 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049491 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050068 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051098 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051484 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051799 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051954 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052429 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25418474 | In contrast, COX-negative cells predominantly harbored mutations in the MT-CO1 and MT-CO3 genes and in regulatory mtDNA elements, but only rarely NADH dehydrogenase mutations |
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