HCSGD entry for MYO1C
1. General information
| Official gene symbol | MYO1C |
|---|---|
| Entrez ID | 4641 |
| Gene full name | myosin IC |
| Other gene symbols | MMI-beta MMIb NMI myr2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IDA | cellular_component |
| GO:0003774 | Motor activity | IEA | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005643 | Nuclear pore | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005902 | Microvillus | IDA | cellular_component |
| GO:0005903 | Brush border | IEA | cellular_component |
| GO:0006605 | Protein targeting | IDA | biological_process |
| GO:0006612 | Protein targeting to membrane | IDA | biological_process |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0009925 | Basal plasma membrane | IDA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IDA | cellular_component |
| GO:0016459 | Myosin complex | IEA | cellular_component |
| GO:0016461 | Unconventional myosin complex | TAS | cellular_component |
| GO:0030335 | Positive regulation of cell migration | IMP | biological_process |
| GO:0031941 | Filamentous actin | IDA | cellular_component |
| GO:0032420 | Stereocilium | IEA | cellular_component |
| GO:0038089 | Positive regulation of cell migration by vascular endothelial growth factor signaling pathway | IMP | biological_process |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045121 | Membrane raft | IDA IEA | cellular_component |
| GO:0045160 | Myosin I complex | IEA | cellular_component |
| GO:0051028 | MRNA transport | IEA | biological_process |
| GO:0060171 | Stereocilium membrane | IEA | cellular_component |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
| GO:0090314 | Positive regulation of protein targeting to membrane | IMP | biological_process |
| GO:1900748 | Positive regulation of vascular endothelial growth factor signaling pathway | IMP | biological_process |
| GO:2000810 | Regulation of tight junction assembly | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8463841609 | 0.0204140040 | 0.9999902473 | 0.2763798665 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6494841633 |
| GSE13712_SHEAR | Up | 0.5518864421 |
| GSE13712_STATIC | Up | 0.5270147050 |
| GSE19018 | Up | 0.1198874378 |
| GSE19899_A1 | Down | -1.1518132828 |
| GSE19899_A2 | Down | -0.6347597959 |
| PubMed_21979375_A1 | Down | -0.2493104477 |
| PubMed_21979375_A2 | Down | -0.0486765632 |
| GSE35957 | Up | 0.0799355553 |
| GSE36640 | Down | -0.3660816483 |
| GSE54402 | Down | -0.4701652831 |
| GSE9593 | Up | 0.1315592524 |
| GSE43922 | Down | -0.4958641947 |
| GSE24585 | Up | 0.2418084139 |
| GSE37065 | Down | -0.4946237014 |
| GSE28863_A1 | Up | 0.1976650500 |
| GSE28863_A2 | Down | -0.1762683457 |
| GSE28863_A3 | Down | -0.5550548759 |
| GSE28863_A4 | Down | -0.0771396755 |
| GSE48662 | Down | -0.0362019675 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025523 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040954 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043155 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047292 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049220 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT050021 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052105 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
