HCSGD entry for NUBP1
1. General information
| Official gene symbol | NUBP1 |
|---|---|
| Entrez ID | 4682 |
| Gene full name | nucleotide binding protein 1 |
| Other gene symbols | NBP NBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006879 | Cellular iron ion homeostasis | IMP | biological_process |
| GO:0010826 | Negative regulation of centrosome duplication | IEA | biological_process |
| GO:0016049 | Cell growth | IMP | biological_process |
| GO:0016226 | Iron-sulfur cluster assembly | IMP | biological_process |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051536 | Iron-sulfur cluster binding | IDA | molecular_function |
| GO:0051539 | 4 iron, 4 sulfur cluster binding | IEA | molecular_function |
| GO:0051642 | Centrosome localization | IEA | biological_process |
| GO:0072697 | Protein localization to cell cortex | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9292953155 | 0.0155873789 | 0.9999902473 | 0.2446159619 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1490346776 |
| GSE13712_SHEAR | Up | 0.0620552864 |
| GSE13712_STATIC | Up | 0.0803760411 |
| GSE19018 | Down | -0.7765849914 |
| GSE19899_A1 | Down | -0.6327242287 |
| GSE19899_A2 | Up | 0.1256936035 |
| PubMed_21979375_A1 | Up | 0.4336104697 |
| PubMed_21979375_A2 | Down | -0.7103324778 |
| GSE35957 | Down | -0.8409909226 |
| GSE36640 | Down | -1.1486410121 |
| GSE54402 | Up | 0.4039339410 |
| GSE9593 | Down | -0.7333470341 |
| GSE43922 | Down | -0.0075192334 |
| GSE24585 | Down | -0.4013568732 |
| GSE37065 | Up | 0.1064475476 |
| GSE28863_A1 | Down | -0.3009521185 |
| GSE28863_A2 | Down | -0.3813659573 |
| GSE28863_A3 | Down | -0.0917908770 |
| GSE28863_A4 | Down | -0.0106306362 |
| GSE48662 | Down | -0.2776872401 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020454 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039853 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042522 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048800 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
