HCSGD entry for NDP

1. General information

Official gene symbolNDP
Entrez ID4693
Gene full nameNorrie disease (pseudoglioma)
Other gene symbolsEVR2 FEVR ND
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001890Placenta developmentIEAbiological_process
GO:0005109Frizzled bindingIPImolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0007033Vacuole organizationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007605Sensory perception of soundNASbiological_process
GO:0008083Growth factor activityTASmolecular_function
GO:0008283Cell proliferationTASbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016055Wnt signaling pathwayIDAbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0035426Extracellular matrix-cell signalingIEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0061299Retina vasculature morphogenesis in camera-type eyeIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00010329770.91264202350.02812626261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2461433806
GSE13712_SHEARDown-0.3433199168
GSE13712_STATICUp0.0513700383
GSE19018Down-0.2095967817
GSE19899_A1Up1.7660398483
GSE19899_A2Up7.5688900199
PubMed_21979375_A1Up6.5447255865
PubMed_21979375_A2Up7.4060159355
GSE35957Down-1.3838307275
GSE36640Up0.7177740319
GSE54402Up3.3147107159
GSE9593Down-0.2420989981
GSE43922Up2.0323141331
GSE24585Up0.0755736064
GSE37065Up1.6849931430
GSE28863_A1Down-0.1515394062
GSE28863_A2Up0.3826442766
GSE28863_A3Up0.2101115487
GSE28863_A4Up0.1126055313
GSE48662Up0.0189768113

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018294MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.