HCSGD entry for NDUFB5
1. General information
| Official gene symbol | NDUFB5 |
|---|---|
| Entrez ID | 4711 |
| Gene full name | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa |
| Other gene symbols | CISGDH SGDH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005747 | Mitochondrial respiratory chain complex I | IDA NAS | cellular_component |
| GO:0006120 | Mitochondrial electron transport, NADH to ubiquinone | NAS | biological_process |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | NAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1538601497 | 0.9259738802 | 0.7807668851 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1888921126 |
| GSE13712_SHEAR | Down | -0.2405878499 |
| GSE13712_STATIC | Down | -0.0201641315 |
| GSE19018 | Up | 0.2363337437 |
| GSE19899_A1 | Up | 0.2199752488 |
| GSE19899_A2 | Up | 0.0254150809 |
| PubMed_21979375_A1 | Up | 0.1924625024 |
| PubMed_21979375_A2 | Up | 0.2322740259 |
| GSE35957 | Down | -0.1961955591 |
| GSE36640 | Up | 0.3926933097 |
| GSE54402 | Up | 0.0486634714 |
| GSE9593 | Down | -0.1498660488 |
| GSE43922 | Down | -0.0788460781 |
| GSE24585 | Up | 0.4315768305 |
| GSE37065 | Up | 0.1526662412 |
| GSE28863_A1 | Up | 0.1857136855 |
| GSE28863_A2 | Up | 0.4297462405 |
| GSE28863_A3 | Down | -0.0139513444 |
| GSE28863_A4 | Up | 0.0006496811 |
| GSE48662 | Down | -0.0897738649 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016164 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024139 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028994 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
