HCSGD entry for NEFH
1. General information
| Official gene symbol | NEFH |
|---|---|
| Entrez ID | 4744 |
| Gene full name | neurofilament, heavy polypeptide |
| Other gene symbols | NFH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005883 | Neurofilament | NAS | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0030424 | Axon | TAS | cellular_component |
| GO:0045110 | Intermediate filament bundle assembly | IEA | biological_process |
| GO:0048936 | Peripheral nervous system neuron axonogenesis | IEA | biological_process |
| GO:0060052 | Neurofilament cytoskeleton organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0786079898 | 0.2173653813 | 0.5909999715 | 0.8973838770 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0406363251 |
| GSE13712_SHEAR | Up | 0.1376808723 |
| GSE13712_STATIC | Down | -0.1104527509 |
| GSE19018 | Up | 0.0421763694 |
| GSE19899_A1 | Up | 0.0181906385 |
| GSE19899_A2 | Up | 0.3163745081 |
| PubMed_21979375_A1 | Up | 0.0836581484 |
| PubMed_21979375_A2 | Up | 0.2949894847 |
| GSE35957 | Down | -1.6578189223 |
| GSE36640 | Down | -3.2936822827 |
| GSE54402 | Down | -0.2136238721 |
| GSE9593 | Down | -0.0633620689 |
| GSE43922 | Up | 0.0269209907 |
| GSE24585 | Up | 2.9046993859 |
| GSE37065 | Down | -0.0313163121 |
| GSE28863_A1 | Down | -0.0199176412 |
| GSE28863_A2 | Up | 0.1043382530 |
| GSE28863_A3 | Up | 0.2305497009 |
| GSE28863_A4 | Up | 0.0816541412 |
| GSE48662 | Down | -0.1812212158 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017917 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020455 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-142-3p | MIMAT0000434 | MIRT021571 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
