HCSGD entry for NEU2
1. General information
| Official gene symbol | NEU2 |
|---|---|
| Entrez ID | 4759 |
| Gene full name | sialidase 2 (cytosolic sialidase) |
| Other gene symbols | SIAL2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006687 | Glycosphingolipid metabolic process | TAS | biological_process |
| GO:0006689 | Ganglioside catabolic process | IDA | biological_process |
| GO:0009313 | Oligosaccharide catabolic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0052794 | Exo-alpha-(2->3)-sialidase activity | IDA | molecular_function |
| GO:0052795 | Exo-alpha-(2->6)-sialidase activity | IEA | molecular_function |
| GO:0052796 | Exo-alpha-(2->8)-sialidase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6539210554 | 0.6566919532 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0569618312 |
| GSE13712_SHEAR | Down | -0.1362737233 |
| GSE13712_STATIC | Up | 0.0942483922 |
| GSE19018 | Down | -0.0464679856 |
| GSE19899_A1 | Down | -0.1312770579 |
| GSE19899_A2 | Up | 0.0339203508 |
| PubMed_21979375_A1 | Down | -0.1151780139 |
| PubMed_21979375_A2 | Down | -0.1925366318 |
| GSE35957 | Up | 0.0254828876 |
| GSE36640 | Up | 0.1358034546 |
| GSE54402 | Down | -0.0793231409 |
| GSE9593 | Down | -0.0204880210 |
| GSE43922 | Up | 0.0274089756 |
| GSE24585 | Up | 0.1457383385 |
| GSE37065 | Down | -0.0963215283 |
| GSE28863_A1 | Up | 0.2266204016 |
| GSE28863_A2 | Up | 0.3019402286 |
| GSE28863_A3 | Up | 0.3754988900 |
| GSE28863_A4 | Down | -0.0966822977 |
| GSE48662 | Up | 0.0151103001 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid | DB03991 | EXPT01111 |
| 5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID | DB07960 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
