HCSGD entry for NHLH2


1. General information

Official gene symbolNHLH2
Entrez ID4808
Gene full namenescient helix loop helix 2
Other gene symbolsHEN2 NSCL2 bHLHa34
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001102RNA polymerase II activating transcription factor bindingIPImolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007417Central nervous system developmentTASbiological_process
GO:0007617Mating behaviorIEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0042698Ovulation cycleIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61948267160.85290135630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0533464791
GSE13712_SHEARDown-0.0221178099
GSE13712_STATICUp0.0734141756
GSE19018Down-0.0537005325
GSE19899_A1Up0.0366661642
GSE19899_A2Up0.1578809359
PubMed_21979375_A1Up0.6479619440
PubMed_21979375_A2Down-0.1199202611
GSE35957Up0.1225269971
GSE36640Up0.0145742133
GSE54402Down-0.0383055109
GSE9593Down-0.0681644566
GSE43922Up0.0533037156
GSE24585Up0.0559852264
GSE37065Down-0.0368784719
GSE28863_A1Down-0.0994018224
GSE28863_A2Up0.2124853357
GSE28863_A3Up0.1370821653
GSE28863_A4Up0.0309014727
GSE48662Down-0.0414685734

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.